Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25515633 | 0.77 | MAP3K14 (0.33) | MAP3K14 | |
| SCHEMBL29960765 | 0.73 | TAAR1 (0.41) | TAAR1 | |
| Hydrochloric Acid SCHEMBL29960613 | 0.72 | TAAR1 (0.41) | TAAR1 | |
| SCHEMBL9146077 | 0.69 | MEN1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL29960779 | 0.68 | TAAR1 (0.44) | TAAR1 | |
| Hydrochloric Acid SCHEMBL29959968 | 0.68 | TAAR1 (0.44) | TAAR1 | |
| SCHEMBL8077337 | 0.68 | ITGB2 (0.31) | — | |
| SCHEMBL29960433 | 0.67 | TAAR1 (0.41) | TAAR1 | |
| SCHEMBL29960123 | 0.67 | — | — | |
| SCHEMBL15903291 | 0.65 | P2RX7 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020578-A1 | ALPHA2C ADRENORECEPTOR AGONISTS | SCHERING CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |