Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8075447 | 0.77 | MAP3K14 (0.43) | MAP3K14 | |
| SCHEMBL25516797 | 0.70 | P2RX7 (0.44) | — | |
| SCHEMBL13377607 | 0.69 | TAAR1 (0.38) | — | |
| SCHEMBL29960765 | 0.69 | TAAR1 (0.41) | — | |
| SCHEMBL12609033 | 0.68 | MAP3K14 (0.42) | MAP3K14 | |
| SCHEMBL12609018 | 0.68 | MAP3K14 (0.42) | MAP3K14 | |
| SCHEMBL802264 | 0.68 | MAP3K14 (0.42) | MAP3K14 | |
| Hydrochloric Acid SCHEMBL29959968 | 0.68 | TAAR1 (0.44) | — | |
| Hydrochloric Acid SCHEMBL29960779 | 0.68 | TAAR1 (0.44) | — | |
| SCHEMBL24895326 | 0.68 | MAP3K14 (0.33) | MAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159543-A1 | ANTHELMINTIC PYRROLOPYRIDAZINE COMPOUNDS | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159543-A1 | ANTHELMINTIC PYRROLOPYRIDAZINE COMPOUNDS | IL5, EPX, MPO | MAP3K14 1050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.