Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8067389 | 0.97 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2USP2L3MBTL1 | |
| SCHEMBL7979212 | 0.83 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2USP2L3MBTL1 | |
| SCHEMBL7976340 | 0.81 | NPC1 (0.45) | NPC1RAB9ANAMPTALDH1A1KMT2A | |
| SCHEMBL8075601 | 0.80 | GAA (0.53) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7979325 | 0.80 | HTT (0.40) | NPC1RAB9ASMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL8063185 | 0.80 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2USP2L3MBTL1 | |
| SCHEMBL8060900 | 0.79 | HPGD (0.40) | NPC1RAB9AALDH1A1KMT2APOLB | |
| SCHEMBL7979456 | 0.79 | CYP1A2 (0.39) | SMN1; SMN2L3MBTL1ALDH1A1KMT2ATDP1 | |
| SCHEMBL7976374 | 0.78 | NPC1 (0.46) | NPC1RAB9AALDH1A1KMT2ATDP1 | |
| SCHEMBL8065554 | 0.78 | HTT (0.36) | NPC1RAB9ASMN1; SMN2L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824514-B1 | DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2000-09-06 | — | — | EP | disclosed |