Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979212 | 0.96 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2USP2L3MBTL1 | |
| SCHEMBL8067389 | 0.83 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2USP2L3MBTL1 | |
| SCHEMBL27493293 | 0.81 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2USP2L3MBTL1 | |
| SCHEMBL7982275 | 0.81 | TAS1R3 (0.46) | NPC1RAB9ASMN1; SMN2NAMPTLMNA | |
| SCHEMBL8075554 | 0.80 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2USP2L3MBTL1 | |
| SCHEMBL7979152 | 0.80 | GAA (0.62) | NPC1RAB9ASMN1; SMN2LMNAPOLB | |
| SCHEMBL27482287 | 0.78 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2USP2L3MBTL1 | |
| SCHEMBL7975941 | 0.76 | KDM4E (0.58) | NPC1RAB9ASMN1; SMN2LMNAPOLB | |
| SCHEMBL7977626 | 0.76 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL7979206 | 0.76 | RAB9A (0.55) | NPC1RAB9ASMN1; SMN2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824514-B1 | DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2000-09-06 | — | — | EP | claimed |
| US-6028100-A | Dihalopropene compounds, insecticides containing them as active ingredients, and intermediates for their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-22 | — | — | US | claimed |