Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17577089 | 0.90 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAALDH1A1MAPTHPGD | |
| SCHEMBL22246694 | 0.89 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAALDH1A1MAPTHPGD | |
| SCHEMBL8077053 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAALDH1A1MAPTHPGD | |
| SCHEMBL11135378 | 0.85 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNAALDH1A1MAPTHPGD | |
| SCHEMBL8071980 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAALDH1A1MAPTHPGD | |
| SCHEMBL24831476 | 0.81 | MAPT (0.45) | SMN1; SMN2LMNAALDH1A1MAPTHPGD | |
| SCHEMBL17563602 | 0.79 | CXCR2 (0.40) | SMN1; SMN2LMNAALDH1A1MAPTHPGD | |
| SCHEMBL18675211 | 0.79 | HSP90AA1 (0.49) | SMN1; SMN2LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL18466753 | 0.78 | CXCR2 (0.39) | SMN1; SMN2LMNAALDH1A1MAPTHPGD | |
| SCHEMBL11799528 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648755-B1 | Improved process for the preparation of 2,4-di(alkylamino)-6-alkylthio-s-triazines and 2-alkylamino-4,6-di(alkylthio)-s-triazines | CIBA SC HOLDING AG (CH) | 2000-08-02 | — | — | EP | disclosed |
| US-5420274-A | Process for the preparation of 2,4-di(alkylamino)-6-alkylthio-s-triazines | CIBA-GEIGY CORPORATION (US) | 1995-05-30 | — | — | US | disclosed |
| EP-0648755-A1 | Improved process for the preparation of 2,4-Di(alkylamino)-6-alkylthio-s-triazines | CIBA-GEIGY AG (CH) | 1995-04-19 | — | — | EP | disclosed |