Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17563602 | 0.92 | CXCR2 (0.40) | SMN1; SMN2LMNAMAPTALDH1A1HPGD | |
| SCHEMBL8075559 | 0.90 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAMAPTALDH1A1HPGD | |
| SCHEMBL18757554 | 0.88 | CXCR2 (0.39) | SMN1; SMN2LMNAMAPTALDH1A1HPGD | |
| SCHEMBL8077053 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAMAPTALDH1A1HPGD | |
| SCHEMBL18466753 | 0.86 | CXCR2 (0.39) | SMN1; SMN2LMNAMAPTALDH1A1HPGD | |
| SCHEMBL17563613 | 0.86 | CXCR2 (0.38) | SMN1; SMN2LMNAMAPTALDH1A1HPGD | |
| SCHEMBL18680416 | 0.83 | CXCR2 (0.40) | SMN1; SMN2LMNAMAPTALDH1A1HPGD | |
| SCHEMBL14869420 | 0.81 | KCNH3 (0.49) | SMN1; SMN2LMNAMAPTALDH1A1HPGD | |
| SCHEMBL17563720 | 0.80 | CXCR2 (0.35) | SMN1; SMN2LMNAMAPTALDH1A1HPGD | |
| SCHEMBL8077020 | 0.79 | KMT2A (0.51) | SMN1; SMN2LMNAMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160068635-A1 | SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME | BATTELLE MEMORIAL INSTITUTE | 2016-03-10 | — | — | US | disclosed |