Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DNM2 | P50570 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17563613 | 0.94 | CXCR2 (0.38) | CXCR2SMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL18757554 | 0.93 | CXCR2 (0.39) | CXCR2SMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL17577089 | 0.92 | SMN1; SMN2 (0.40) | CXCR2SMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL18466753 | 0.91 | CXCR2 (0.39) | CXCR2SMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL18680416 | 0.90 | CXCR2 (0.40) | CXCR2SMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL17563720 | 0.87 | CXCR2 (0.35) | CXCR2SMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL8077020 | 0.87 | KMT2A (0.51) | CXCR2SMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL22246694 | 0.86 | SMN1; SMN2 (0.47) | CXCR2SMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL24831477 | 0.86 | DNM2 (0.46) | KMT2ADNM2 | |
| SCHEMBL8072012 | 0.83 | DNM2 (0.48) | CXCR2SMN1; SMN2LMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016036847-A9 | SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME | BATTELLE MEMORIAL INSTITUTE (US) | 2017-04-20 | — | — | WO | disclosed |
| US-20170088671-A1 | SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME | BATTELLE MEMORIAL INSTITUTE (US) | 2017-03-30 | — | — | US | disclosed |
| US-9562137-B2 | Synthetic polymers and methods of making and using the same | BATTELLE MEMORIAL INSTITUTE (US) | 2017-02-07 | — | — | US | disclosed |
| US-20160257785-A1 | SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME | U.S. DEPARTMENT OF ENERGY | 2016-09-08 | — | — | US | disclosed |
| US-9365676-B2 | Synthetic polymers and methods of making and using the same | BATTELLE MEMORIAL INSTITUTE (US) | 2016-06-14 | — | — | US | disclosed |
| US-20160068635-A1 | SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME | BATTELLE MEMORIAL INSTITUTE | 2016-03-10 | — | — | US | disclosed |
| WO-2016036847-A1 | SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME | BATTELLE MEMORIAL INSTITUTE (US) | 2016-03-10 | — | — | WO | disclosed |