SCHEMBL8075769

COc1ccc(CCCCCCCCOc2ccc(CSc3cccc(NS(=O)(=O)C(F)(F)F)c3)nc2C=CC(=O)O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	LTB4R	Q15722	20/20	1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8076054	0.90	LTB4R (1.00)	LTB4R
SCHEMBL8073512	0.88	LTB4R (0.79)	LTB4R
SCHEMBL9333850	0.88	LTB4R (0.78)	LTB4R
SCHEMBL8862038	0.86	LTB4R (1.00)	LTB4R
SCHEMBL8862133	0.86	LTB4R (1.00)	LTB4R
SCHEMBL8862135	0.85	LTB4R (1.00)	LTB4R
SCHEMBL8075116	0.84	LTB4R (1.00)	LTB4R
SCHEMBL8075117	0.84	LTB4R (1.00)	LTB4R
SCHEMBL8862050	0.84	LTB4R (1.00)	LTB4R
SCHEMBL8080163	0.84	LTB4R (1.00)	LTB4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0812194-B1	Use of substituted pyridine compounds for treating atopic dermatitis and contact dermatitis	SMITHKLINE BEECHAM CORP (US)	2000-08-16	—	—	EP	disclosed
US-5656636-A	TREATING PSORIASIS	SMITHKLINE BEECHAM CORPORATION (US)	1997-08-12	—	—	US	disclosed
US-5633258-A	Pyridine compounds for treating leukotriene-related diseases	SMITHKLINE BEECHAM CORPORATION (US)	1997-05-27	—	—	US	disclosed
US-5631262-A	Pyridine compounds for treating leukotriene-related diseases	SMITHKLINE BEECHAM CORPORATION (US)	1997-05-20	—	—	US	disclosed