SCHEMBL8075807

SCHEMBL8075807

CCCC[Sn](CCCC)(CCCC)c1ccsc1C=O

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6036190 0.78 ALDH1A1 (0.33) LMNA
SCHEMBL15168859 0.75
SCHEMBL1396162 0.75
SCHEMBL17644605 0.74 ALDH1A1 (0.32)
SCHEMBL8075810 0.73 CYP2A6 (0.32)
SCHEMBL17240323 0.72 NPC1 (0.33) MEN1KMT2A
SCHEMBL6819727 0.70 TYR (0.38) MEN1KMT2ALMNA
SCHEMBL6288871 0.69 TDP1 (0.41) MEN1KMT2ALMNA
SCHEMBL18825997 0.69 HIF1A (0.40) MEN1KMT2A
SCHEMBL9305102 0.69 KEAP1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2000247968-A POLYARYL ANTI-TUMOR AGENT IND TECHNOL RES INST 2000-09-12 JP disclosed