Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.60 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.60 |
| ▸ | PRKCB | P05771 | 4/20 | 0.57 |
| ▸ | PRKCA | P17252 | 4/20 | 0.57 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.57 |
| ▸ | PRKCH | P24723 | 1/20 | 0.57 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.57 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.57 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.56 |
| ▸ | CDK4 | P11802 | 2/20 | 0.56 |
| ▸ | CCND1 | P24385 | 2/20 | 0.56 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.56 |
| ▸ | CDK2 | P24941 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8079978 | 0.99 | PIM1 (0.59) | PIM1CAMK2DPRKCBPRKCAPRKCD | |
| Hydrochloric Acid SCHEMBL8074734 | 0.91 | PRKCB (0.61) | PIM1CAMK2DPRKCBPRKCAPRKCD | |
| SCHEMBL8075459 | 0.86 | PIM1 (0.70) | PIM1CAMK2DPRKCBPRKCAPRKCD | |
| SCHEMBL8065185 | 0.85 | PRKCA (0.68) | PIM1CAMK2DPRKCBPRKCAPRKCD | |
| Hydrochloric Acid SCHEMBL8064918 | 0.84 | PRKCA (0.67) | PIM1CAMK2DPRKCBPRKCAPRKCD | |
| SCHEMBL8075731 | 0.84 | PIM1 (0.70) | PIM1CAMK2DPRKCACCNE2CDK4 | |
| SCHEMBL8074992 | 0.82 | PRKCA (0.63) | PIM1CAMK2DPRKCBPRKCAPRKCD | |
| SCHEMBL8073838 | 0.81 | CCNE2 (0.66) | PIM1CAMK2DPRKCACCNE2CDK4 | |
| SCHEMBL8167903 | 0.81 | CCNE2 (0.72) | PIM1CAMK2DPRKCACCNE2CDK4 | |
| SCHEMBL8072942 | 0.81 | CCNE2 (0.62) | PIM1CAMK2DPRKCACCNE2CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153641-A | Pharmaceutically active compounds | ASTRA AKTIEBOLAG (SE) | 2000-11-28 | — | — | US | disclosed |
| EP-0925296-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | Astra Aktiebolag (SE) | 1999-06-30 | — | — | EP | disclosed |
| WO-1998011102-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRA AKTIEBOLAG (SE) | 1998-03-19 | — | — | WO | disclosed |