Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28488116 | 0.88 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9ALMNATP53 | |
| Hydrochloric Acid SCHEMBL28640787 | 0.86 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9ALMNATP53 | |
| SCHEMBL5023451 | 0.86 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1RAB9ALMNATP53 | |
| SCHEMBL11613440 | 0.80 | RAB9A (0.59) | SMN1; SMN2NPC1RAB9ALMNATP53 | |
| SCHEMBL11727782 | 0.80 | TSHR (0.49) | SMN1; SMN2NPC1RAB9ALMNATP53 | |
| SCHEMBL21753481 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9ALMNATP53 | |
| SCHEMBL2939270 | 0.79 | NPC1 (0.75) | SMN1; SMN2NPC1RAB9ALMNATP53 | |
| SCHEMBL27802492 | 0.79 | RAB9A (0.57) | SMN1; SMN2NPC1RAB9ALMNATP53 | |
| SCHEMBL16484012 | 0.78 | NPC1 (0.51) | SMN1; SMN2NPC1RAB9ALMNATP53 | |
| SCHEMBL2457113 | 0.77 | PDE10A (0.62) | SMN1; SMN2TSHRKDM4ENPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019722-A1 | POLYMERIC FLUOROPHORES ENHANCED BY MOIETIES PROVIDING A HYDROPHOBIC AND CONFORMATIONALLY RESTRICTIVE MICROENVIRONMENT | Abbott Laboratories (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1997028447-A1 | POLYMERIC FLUOROPHORES ENHANCED BY MOIETIES PROVIDING A HYDROPHOBIC AND CONFORMATIONALLY RESTRICTIVE MICROENVIRONMENT | ABBOTT LABORATORIES (US) | 1997-08-07 | — | — | WO | disclosed |