Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 7/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | DDR1 | Q08345 | 9/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL794413 | 1.00 | P2RX7 (0.39) | P2RX7EPHX2DDR1KCNH2 | |
| SCHEMBL15467820 | 0.95 | P2RX7 (0.40) | P2RX7EPHX2DDR1KCNH2 | |
| SCHEMBL17874615 | 0.90 | EPHX2 (0.45) | P2RX7EPHX2KCNH2 | |
| SCHEMBL17874614 | 0.88 | DDR1 (0.38) | P2RX7EPHX2DDR1 | |
| SCHEMBL15474191 | 0.84 | P2RX7 (0.38) | P2RX7EPHX2DDR1 | |
| SCHEMBL794251 | 0.84 | P2RX7 (0.38) | P2RX7EPHX2DDR1 | |
| SCHEMBL17874619 | 0.83 | CYP2D6 (0.40) | EPHX2KCNH2 | |
| SCHEMBL17874618 | 0.82 | P2RX7 (0.37) | P2RX7EPHX2DDR1 | |
| SCHEMBL15474190 | 0.81 | EPHX2 (0.35) | P2RX7EPHX2 | |
| SCHEMBL795264 | 0.81 | EPHX2 (0.35) | P2RX7EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9375000-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-28 | — | — | US | disclosed |
| US-9375000-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-28 | — | — | US | disclosed |
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-02-13 | — | — | US | disclosed |
| WO-2012035011-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2012-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | DDT, ACHE, CAT | P2RX7 750/4885EPHX2 1332/4885DDR1 4208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.