Quinolinic Acid

Quinolinic Acid

SCHEMBL8076149

O=C([O-])c1cccnc1C(=O)[O-].O=C([O-])c1cccnc1C(=O)[O-].O=C([O-])c1cccnc1C(=O)[O-].[Fe+3].[Fe+3]

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.53
ALDH1A1 P00352 4/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
MAPT P10636 2/20 0.53
CYP3A4 P08684 1/20 0.53
ALOX15 P16050 1/20 0.53
TSHR P16473 1/20 0.53
BLM P54132 1/20 0.53
AGER Q15109 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
TDP1 Q9NUW8 1/20 0.45
NAPRT Q6XQN6 2/20 0.42
LMNA P02545 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HPGD P15428 1/20 0.42
CYP1A2 P05177 1/20 0.39
PARP1 P09874 1/20 0.39
P2RX7 Q99572 1/20 0.38
GAA P10253 1/20 0.37
CNR2 P34972 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinolinic Acid SCHEMBL5361017 0.96 KDM4E (0.53) KDM4EALDH1A1L3MBTL1MAPTCYP3A4
Quinolinic Acid SCHEMBL29358561 0.96 KDM4E (0.53) KDM4EALDH1A1L3MBTL1MAPTCYP3A4
Quinolinic Acid SCHEMBL28576614 0.96 KDM4E (0.53) KDM4EALDH1A1L3MBTL1MAPTCYP3A4
Quinolinic Acid SCHEMBL5381550 0.96 KDM4E (0.53) KDM4EALDH1A1L3MBTL1MAPTCYP3A4
Quinolinic Acid SCHEMBL15401426 0.96 KDM4E (0.53) KDM4EALDH1A1L3MBTL1MAPTCYP3A4
Quinolinic Acid SCHEMBL5674127 0.96 KDM4E (0.53) KDM4EALDH1A1L3MBTL1MAPTCYP3A4
Quinolinic Acid SCHEMBL1897907 0.96 KDM4E (0.53) KDM4EALDH1A1L3MBTL1MAPTCYP3A4
Quinolinic Acid SCHEMBL11408577 0.96 KDM4E (0.53) KDM4EALDH1A1L3MBTL1MAPTCYP3A4
Quinolinic Acid SCHEMBL11408572 0.96 KDM4E (0.53) KDM4EALDH1A1L3MBTL1MAPTCYP3A4
Quinolinic Acid SCHEMBL3425488 0.96 KDM4E (0.53) KDM4EALDH1A1L3MBTL1MAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0602600-B1 Photographic persulfate bleaches with ferric catalysts EASTMAN KODAK CO (US) 2000-07-26 EP disclosed
US-5536625-A FORMING COLOR IMAGES AFTER EXPOSURE AND DEVELOPMENT FOR SILVER HALIDE EMULSIONS EASTMAN KODAK COMPANY (US) 1996-07-16 US disclosed
US-5460924-A Accelerator for bleaching silver halide emulsions EASTMAN KODAK COMPANY (US) 1995-10-24 US disclosed
EP-0602600-A2 Photographic persulfate bleaches with ferric catalysts EASTMAN KODAK COMPANY (US) 1994-06-22 EP disclosed