Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25985239 | 0.80 | SMN1; SMN2 (0.45) | GAASMN1; SMN2RAB9AKMT2AL3MBTL1 | |
| SCHEMBL8072335 | 0.79 | HRH3 (0.43) | SMN1; SMN2KMT2A | |
| SCHEMBL10974437 | 0.76 | PIK3CD (0.44) | RAB9AKMT2AL3MBTL1PIK3CD | |
| SCHEMBL10977910 | 0.74 | PIK3CD (0.45) | RAB9AKMT2AL3MBTL1NPC1PIK3CD | |
| SCHEMBL8015523 | 0.74 | PIK3CD (0.45) | RAB9AKMT2ANPC1GFERPIK3CD | |
| SCHEMBL25633842 | 0.74 | KMT2A (0.43) | GAASMN1; SMN2RAB9AKMT2AL3MBTL1 | |
| SCHEMBL628723 | 0.73 | PIK3CD (0.50) | RAB9AKMT2AL3MBTL1PIK3CD | |
| SCHEMBL9812335 | 0.73 | PIK3CD (0.50) | RAB9AKMT2AL3MBTL1PIK3CD | |
| SCHEMBL10974005 | 0.72 | PIK3CD (0.39) | SMN1; SMN2RAB9AKMT2AL3MBTL1PIK3CD | |
| SCHEMBL10978986 | 0.72 | L3MBTL1 (0.41) | SMN1; SMN2RAB9AKMT2AL3MBTL1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121270-A | N-(EPOXYALKYL)XANTHINE DERIVATIVES WHICH MODULATE CELLULAR RESPONSES TO NOXIOUS, PRO-INFLAMMATORY STIMULI | CELL THERAPEUTICS, INC. (US) | 2000-09-19 | — | — | US | disclosed |
| US-5866576-A | COMPOUNDS THAT ACT AS DRUGS ON THE CELLULAR AND BIOCHEMICAL LEVEL TO MODULATE CELLULAR RESPONSES TO NOXIOUS, PRO-INFLAMMATORY STIMULI. | CELL THERAPEUTICS, INC. (US) | 1999-02-02 | — | — | US | disclosed |