Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.60 |
| ▸ | FASN | P49327 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 3/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28048555 | 0.88 | DYRK1A (0.72) | DYRK1AFASNALDH1A1GAAMEN1 | |
| SCHEMBL9224654 | 0.84 | DYRK1A (0.55) | DYRK1AALDH1A1GAAMEN1KMT2A | |
| SCHEMBL29687792 | 0.84 | DYRK1A (0.49) | DYRK1AALDH1A1GAAMEN1KMT2A | |
| SCHEMBL423908 | 0.84 | DYRK1A (0.49) | DYRK1AALDH1A1GAAMEN1KMT2A | |
| SCHEMBL592989 | 0.83 | DYRK1A (0.62) | DYRK1AFASNALDH1A1GAAMEN1 | |
| SCHEMBL29375136 | 0.83 | DYRK1A (0.62) | DYRK1AFASNALDH1A1GAAMEN1 | |
| SCHEMBL8076216 | 0.81 | DYRK1A (0.60) | DYRK1AFASNALDH1A1GAAMEN1 | |
| SCHEMBL27606654 | 0.81 | DYRK1A (0.60) | DYRK1AFASNALDH1A1GAAMEN1 | |
| SCHEMBL8080835 | 0.81 | DYRK1A (0.60) | DYRK1AFASNALDH1A1GAAMEN1 | |
| SCHEMBL645873 | 0.81 | DYRK1A (0.60) | DYRK1AFASNALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3116851-B1 | ANALOGS OF FEXARAMINE AND METHODS OF MAKING AND USING | SALK INST FOR BIOLOGICAL STUDI (US) | 2023-07-26 | — | — | EP | disclosed |
| WO-2017078927-A1 | ANALOGS OF FEXARAMINE AND METHODS OF MAKING AND USING | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2017-05-11 | — | — | WO | disclosed |
| US-20170066724-A1 | ANALOGS OF FEXARAMINE AND METHODS OF MAKING AND USING | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2017-03-09 | — | — | US | disclosed |
| CN-103739565-B | Method for synthesizing medicament intermediate benzoxazine ketone derivative | 2ND AFFILIATED HOSPITAL & YUYING CHILDREN S HOSPITAL OF WENZHOU MEDICAL UNIVERSITY | 2015-06-03 | — | — | CN | disclosed |
| CN-103739565-A | Method for synthesizing medicament intermediate benzoxazine ketone derivative | 2ND AFFILIATED HOSPITAL & YUYING CHILDREN S HOSPITAL OF WENZHOU MEDICAL UNIVERSITY | 2014-04-23 | — | — | CN | disclosed |
| US-4917997-A | MIXED WITH ASCORBIC ACID COMPONENT, SENSITIZING DYE, BISAMINOSTILBENE WITH PYRIMIDINE SUBSTITUTION | FUJI PHOTO FILM CO., LTD. (JP) | 1990-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170066724-A1 | ANALOGS OF FEXARAMINE AND METHODS OF MAKING AND USING | FXR2, FXR1, SLC10A2 | DYRK1A 1655/4885FASN 347/4885ALDH1A1 1412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.