SCHEMBL8076227

SCHEMBL8076227

FC=COC1CCCCC1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
CA12 O43570 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1475813 0.76 ACHE (0.31) CA1CA2CA12CA9
SCHEMBL4030169 0.76 ACHE (0.31) CA1CA2CA12CA9
SCHEMBL3942990 0.76 ACHE (0.31) CA1CA2CA12CA9
SCHEMBL15227532 0.76 ACHE (0.31) CA1CA2CA12CA9
SCHEMBL1475814 0.76 ACHE (0.31) CA1CA2CA12CA9
SCHEMBL3942982 0.76 ACHE (0.31) CA1CA2CA12CA9
SCHEMBL6181352 0.73 CA1 (0.36) CA1CA2CA12CA9
SCHEMBL11797442 0.72
SCHEMBL3943541 0.72
SCHEMBL3943548 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6080452-A IMPROVED RESPONSE MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2000-06-27 US disclosed
US-5919396-A POSITIVE DIELECTRIC ANISOTROPY; ADJUSTMENT LAYER MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1999-07-06 US disclosed