SCHEMBL8076232

SCHEMBL8076232

C=CCCCc1ccccc1CC

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 1/20 0.45
THRA P10827 1/20 0.40
THRB P10828 1/20 0.40
ALDH1A1 P00352 2/20 0.39
TSHR P16473 2/20 0.39
USP2 O75604 1/20 0.37
HPGD P15428 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CYP4F2 P78329 1/20 0.36
CYP4A11 Q02928 1/20 0.36
GABRA1 P14867 2/20 0.35
GABRB2 P47870 2/20 0.35
LIPG Q9Y5X9 1/20 0.35
LMNA P02545 1/20 0.34
EP300 Q09472 1/20 0.33
KAT2B Q92831 1/20 0.33
KAT5 Q92993 1/20 0.33
KAT8 Q9H7Z6 1/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8076094 0.94 ALDH1A1 (0.43) TLR8THRATHRBALDH1A1TSHR
SCHEMBL8063272 0.92 USP2 (0.46) TLR8THRATHRBALDH1A1TSHR
SCHEMBL8073318 0.92 USP2 (0.46) TLR8THRATHRBALDH1A1TSHR
SCHEMBL8062344 0.92 USP2 (0.46) TLR8THRATHRBALDH1A1TSHR
SCHEMBL8076164 0.92 USP2 (0.46) TLR8THRATHRBALDH1A1TSHR
SCHEMBL8077547 0.88 TLR8 (0.45) TLR8THRATHRBALDH1A1TSHR
SCHEMBL8063252 0.88 TSHR (0.50) TLR8THRATHRBALDH1A1TSHR
SCHEMBL8072326 0.88 GABRA1 (0.38) TLR8THRATHRBALDH1A1TSHR
SCHEMBL12802676 0.83 TLR8 (0.39) TLR8THRATHRBALDH1A1TSHR
SCHEMBL12802315 0.82 GABRA1 (0.39) TLR8THRATHRBALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9587042-B2 Process for producing modified conjugated diene-based polymer, modified conjugated diene-based polymer, and polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-03-07 US disclosed
CN-102731722-B For the production of the method for modified conjugated diene polymer, modified conjugated diene polymer and polymer composition SUMITOMO CHEMICAL CO., LTD. (JP) 2016-03-16 CN disclosed
US-8933165-B2 Method for producing modified conjugated diene-based polymer, and method for producing polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-01-13 US disclosed
US-8835564-B2 Method for producing modified conjugated diene-based polymer, and method for producing polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-09-16 US disclosed
US-20140088256-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE-BASED POLYMER, AND METHOD FOR PRODUCING POLYMER COMPOSITION ZEON CORPORATION (JP) 2014-03-27 US disclosed
US-20140088242-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE-BASED POLYMER, AND METHOD FOR PRODUCING POLYMER COMPOSITION ZEON CORPORATION (JP) 2014-03-27 US disclosed
CN-102731722-A Process for producing modified conjugated diene-based polymer, modified conjugated diene-based polymer, and polymer composition SUMITOMO CHEMICAL CO 2012-10-17 CN disclosed
US-20120252966-A1 PROCESS FOR PRODUCING MODIFIED CONJUGATED DIENE-BASED POLYMER, MODIFIED CONJUGATED DIENE-BASED POLYMER, AND POLYMER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED 2012-10-04 US disclosed
EP-1363629-B1 KAPPA OPIOID RECEPTOR LIGANDS RES TRIANGLE INST (US) 2009-09-16 EP disclosed
US-6063940-A Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-05-16 US disclosed
US-4764584-A Radiation-sensitive polycondensates, their preparation, material coated therewith and the use thereof CIBA-GEIGY CORPORATION (US) 1988-08-16 US disclosed
US-4714669-A POLYAMIDES, POLYESTERS, OR POLYESTER AMIDES CIBA-GEIGY CORPORATION (US) 1987-12-22 US disclosed
US-4698295-A AUTOMATIC PHOTOCROSSLINKING CIBA-GEIGY CORPORATION (US) 1987-10-06 US disclosed
US-4696890-A POLYIMIDES BY HEATING A PHOTOCROSSLINKED POLYAMIC ESTER CIBA-GEIGY CORPORATION (US) 1987-09-29 US disclosed
US-4694061-A POLYAMIDE(IMIDE)S CONTAINING BENZOPHENONE (DI-ORTRI)CARBOXYLIC ACID CIBA-GEIGY CORPORATION (US) 1987-09-15 US disclosed
US-4680195-A POLYIMIDES WITH AROMATIC KETONE GROUPS, RELIEF IMAGES CIBA-GEIGY CORPORATION (US) 1987-07-14 US disclosed
US-4677186-A AMINO DICARBOXYLIC ACID MONOMERS, PROTECITVE COATINGS CIBA-GEIGY CORPORATION (US) 1987-06-30 US disclosed
US-4657832-A HOMO-AND COPOLYMERS, OF POLYIMIDES, POLYAMIDES, POLYESTERS AND OTHERS CIBA-GEIGY CORPORATION (US) 1987-04-14 US disclosed
US-4629685-A PROTECTIVE FILMS OR PHOTOGRAPHIC RELIEF IMAGES CIBA-GEIGY CORPORATION (US) 1986-12-16 US disclosed
US-4629777-A RADIATION-SENSITIVE, AUTOPHOTOCROSSLINKABLE; FILMS, COATINGS CIBA-GEIGY CORPORATION (US) 1986-12-16 US disclosed