SCHEMBL8076303

SCHEMBL8076303

CCCCC(N)CS(=O)(=O)O

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.50
S1PR2 O95136 6/20 0.41
S1PR1 P21453 6/20 0.41
S1PR3 Q99500 6/20 0.41
S1PR4 O95977 4/20 0.40
DPP7 Q9UHL4 1/20 0.40
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
SLC1A3 P43003 1/20 0.37
SLC1A2 P43004 1/20 0.37
SLC1A1 P43005 1/20 0.37
ALDH1A1 P00352 1/20 0.37
LAP3 P28838 2/20 0.36
SLC15A1 P46059 1/20 0.36
FDPS P14324 1/20 0.35
PLA2G1B P04054 1/20 0.35
PLA2G2A P14555 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8076301 1.00 TP53 (0.50) TP53S1PR2S1PR1S1PR3S1PR4
SCHEMBL28803665 0.94 TP53 (0.59) TP53S1PR2S1PR1S1PR3S1PR4
SCHEMBL27662459 0.92 TP53 (0.57) TP53S1PR2S1PR1S1PR3S1PR4
SCHEMBL27784488 0.92 TP53 (0.57) TP53S1PR2S1PR1S1PR3S1PR4
SCHEMBL9657411 0.92 TP53 (0.57) TP53S1PR2S1PR1S1PR3S1PR4
SCHEMBL7552156 0.92 TP53 (0.57) TP53S1PR2S1PR1S1PR3S1PR4
SCHEMBL28061348 0.92 TP53 (0.57) TP53S1PR2S1PR1S1PR3S1PR4
SCHEMBL28083774 0.81 ALDH1A1 (0.42) TP53S1PR2S1PR1S1PR3DPP7
SCHEMBL353077 0.81 S1PR2 (0.59) TP53S1PR2S1PR1S1PR3S1PR4
SCHEMBL8748124 0.80 APP (0.46) TP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105431571-A Organic disulfide based corrosion inhibitors ECOLAB USA INC 2016-03-23 CN claimed
CN-105431571-A Organic disulfide based corrosion inhibitors ECOLAB USA INC 2016-03-23 CN disclosed
EP-0555537-B1 Endothelin antagonists BANYU PHARMA CO LTD (JP) 2000-11-02 EP disclosed
US-5614498-A OLIGOPEPTIDES, BRONCHDILATORS BANYU PHARMACEUTICAL CO., LTD. (JP) 1997-03-25 US disclosed
US-5496928-A Endothelin antagonistic substance BANYU PHARMACEUTICAL CO., LTD. (JP) 1996-03-05 US disclosed
EP-0555537-A2 Endothelin antagonistic substance BANYU PHARMACEUTICAL CO., LTD. (JP) 1993-08-18 EP disclosed