Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8748129 | 0.93 | APP (0.44) | APPBLMLMNASLC6A6CYP2C19 | |
| SCHEMBL584136 | 0.86 | LMNA (0.42) | APPBLMLMNASLC6A6CYP2C19 | |
| SCHEMBL1133365 | 0.84 | LMNA (0.40) | APPBLMLMNASLC6A6CYP2C19 | |
| SCHEMBL27810744 | 0.80 | LTA4H (0.33) | APPLTA4HTP53SLC22A6ENPEP | |
| SCHEMBL28472596 | 0.80 | TP53 (0.36) | APPLTA4HTP53SLC22A6ENPEP | |
| SCHEMBL8076303 | 0.80 | TP53 (0.50) | TP53ALDH1A1 | |
| SCHEMBL8076301 | 0.80 | TP53 (0.50) | TP53ALDH1A1 | |
| SCHEMBL28803665 | 0.78 | TP53 (0.59) | TP53ALDH1A1 | |
| SCHEMBL7552156 | 0.77 | TP53 (0.57) | BLMLMNATP53GMNNALDH1A1 | |
| SCHEMBL9657411 | 0.77 | TP53 (0.57) | BLMLMNATP53GMNNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109868107-A | A kind of adhesive and its preparation method and application | 万华化学（宁波）有限公司 | 2019-06-11 | — | — | CN | claimed |
| EP-0467856-B1 | Aminoalkanesulfonic acid derivatives and pharmaceutical compositions for use in preventing or treating heart diseases | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 1997-03-19 | — | — | EP | claimed |
| EP-0467856-A2 | Aminoalkanesulfonic acid derivatives and pharmaceutical compositions for use in preventing or treating heart diseases | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1992-01-22 | — | — | EP | claimed |
| CN-109942787-A | A kind of polyurethane-polyurea water dispersion and preparation method thereof and its application in water-borne wood coating | 万华化学（宁波）有限公司 | 2019-06-28 | — | — | CN | disclosed |
| EP-0467856-B1 | Aminoalkanesulfonic acid derivatives and pharmaceutical compositions for use in preventing or treating heart diseases | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 1997-03-19 | — | — | EP | disclosed |
| US-5430052-A | Protective effect against myocardial disorders caused by calcium ion overload; antiischemic agents; remedy for heart failure, angina pectoris | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1995-07-04 | — | — | US | disclosed |
| EP-0467856-A2 | Aminoalkanesulfonic acid derivatives and pharmaceutical compositions for use in preventing or treating heart diseases | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1992-01-22 | — | — | EP | disclosed |