Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9427405 | 0.94 | NPC1 (0.49) | NPC1RAB9AKMT2AMEN1L3MBTL1 | |
| SCHEMBL8083816 | 0.83 | ALDH1A1 (0.46) | L3MBTL1KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL31569325 | 0.82 | NPC1 (0.61) | NPC1RAB9AKMT2AMEN1CASP3 | |
| SCHEMBL8083786 | 0.81 | NPC1 (0.52) | NPC1RAB9ACASP3MGLLSMN1; SMN2 | |
| SCHEMBL8083691 | 0.80 | NPC1 (0.44) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL9407131 | 0.78 | ALDH1A1 (0.48) | NPC1RAB9AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL8959300 | 0.78 | CUL4A (0.42) | NPC1RAB9AKMT2AKDM4EALDH1A1 | |
| SCHEMBL8760807 | 0.78 | POLB (0.43) | NPC1RAB9AKMT2AMEN1L3MBTL1 | |
| SCHEMBL9407126 | 0.77 | NPSR1 (0.51) | NPC1RAB9AKMT2AMEN1L3MBTL1 | |
| SCHEMBL9427678 | 0.76 | ALDH1A1 (0.52) | NPC1RAB9AKMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0493606-B1 | HETEROCYCLE-SUBSTITUTED BENZENE DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT | SAGAMI CHEM RES (JP) | 2000-10-18 | — | — | EP | disclosed |
| EP-1006105-A1 | Benzene derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2000-06-07 | — | — | EP | disclosed |
| US-5464811-A | Benzene derivatives substituted with heterocyclic ring and herbicides containing same as active ingredients | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-11-07 | — | — | US | disclosed |
| US-5424277-A | An N-substituted-3,4,5,6-tetrahydrophthalimide derivative characterized by having a cycloalkoxy group at the 5-position of the phenyl ring on the nitrogen | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-06-13 | — | — | US | disclosed |
| EP-0493606-A1 | HETEROCYCLE-SUBSTITUTED BENZENE DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-07-08 | — | — | EP | disclosed |