Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 5/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31569325 | 0.86 | NPC1 (0.61) | NPC1RAB9AMGLLMAOBPOLB | |
| SCHEMBL4264049 | 0.85 | NPC1 (0.56) | NPC1RAB9AMGLLMAOBPOLB | |
| SCHEMBL9427405 | 0.84 | NPC1 (0.49) | NPC1RAB9AMGLLMAOBPOLB | |
| SCHEMBL12892596 | 0.81 | RAB9A (0.57) | NPC1RAB9AMGLLMAOBPOLB | |
| SCHEMBL8076434 | 0.81 | NPC1 (0.49) | NPC1RAB9AMGLLMAOBCASP3 | |
| SCHEMBL8084401 | 0.80 | ALDH1A1 (0.51) | NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL24707414 | 0.80 | NPC1 (0.52) | NPC1RAB9AMGLLMAOBPOLB | |
| SCHEMBL30001291 | 0.80 | NPC1 (0.52) | NPC1RAB9AMGLLMAOBPOLB | |
| SCHEMBL3986319 | 0.79 | NPC1 (0.55) | NPC1RAB9AMGLLMAOBPOLB | |
| SCHEMBL5945330 | 0.79 | NPC1 (0.55) | NPC1RAB9AMGLLMAOBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0493606-B1 | HETEROCYCLE-SUBSTITUTED BENZENE DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT | SAGAMI CHEM RES (JP) | 2000-10-18 | — | — | EP | disclosed |
| EP-1006105-A1 | Benzene derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2000-06-07 | — | — | EP | disclosed |
| US-5464811-A | Benzene derivatives substituted with heterocyclic ring and herbicides containing same as active ingredients | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-11-07 | — | — | US | disclosed |
| US-5424277-A | An N-substituted-3,4,5,6-tetrahydrophthalimide derivative characterized by having a cycloalkoxy group at the 5-position of the phenyl ring on the nitrogen | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-06-13 | — | — | US | disclosed |
| EP-0493606-A1 | HETEROCYCLE-SUBSTITUTED BENZENE DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-07-08 | — | — | EP | disclosed |