Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 3/20 | 0.53 |
| ▸ | EGFR | P00533 | 3/20 | 0.53 |
| ▸ | ABL2 | P42684 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 2/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8076523 | 0.88 | MEN1 (0.64) | KMT2AMEN1RAB9ANPC1NR2F2 | |
| SCHEMBL17406893 | 0.88 | KMT2A (0.65) | KMT2AMEN1RAB9ANPC1NR2F2 | |
| SCHEMBL8088051 | 0.87 | MEN1 (0.63) | KMT2AMEN1RAB9ANPC1NR2F2 | |
| SCHEMBL8084587 | 0.83 | KMT2A (0.67) | KMT2AMEN1RAB9ANPC1NR2F2 | |
| SCHEMBL19327466 | 0.83 | POLB (0.66) | KMT2AMEN1RAB9ANPC1NR2F2 | |
| SCHEMBL8088017 | 0.79 | MKNK1 (0.54) | RAB9ANPC1KDM4EMAPK1HTT | |
| SCHEMBL3260247 | 0.79 | KMT2A (0.50) | KMT2AMEN1RAB9ANPC1NR2F2 | |
| SCHEMBL3157350 | 0.78 | MEN1 (1.00) | KMT2AMEN1RAB9ANPC1NR2F2 | |
| SCHEMBL19327436 | 0.76 | POLB (0.56) | KMT2AMEN1RAB9ANPC1NR2F2 | |
| SCHEMBL3259092 | 0.75 | KMT2A (0.64) | KMT2AMEN1RAB9ANPC1NR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096749-A | ANTITUMOR, EPIDERMAL GROWTH FACTOR | NOVARTIS CORPORATION (US) | 2000-08-01 | — | — | US | disclosed |