Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPO | P22079 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722623 | 0.80 | LPO (0.41) | LPOHTTFDPSKMT2AMEN1 | |
| SCHEMBL8088201 | 0.74 | LPO (0.36) | LPOFDPSKMT2AALDH1A1 | |
| SCHEMBL8084747 | 0.72 | LPO (0.41) | LPOHTTFDPSKMT2AMEN1 | |
| SCHEMBL6345915 | 0.71 | LPO (0.48) | LPOHTTFDPSKMT2AMEN1 | |
| SCHEMBL5093089 | 0.70 | LPO (0.43) | LPOHTTFDPSKMT2AMEN1 | |
| SCHEMBL6829172 | 0.69 | LPO (0.46) | LPOHTTFDPSKMT2AMEN1 | |
| SCHEMBL13946295 | 0.67 | KMT2A (0.44) | LPOHTTFDPSKMT2AMEN1 | |
| SCHEMBL22863247 | 0.67 | KMT2A (0.44) | LPOHTTFDPSKMT2AMEN1 | |
| SCHEMBL10288648 | 0.67 | KMT2A (0.44) | LPOHTTFDPSKMT2AMEN1 | |
| SCHEMBL27792290 | 0.65 | LPO (0.39) | LPOHTTFDPSKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1050536-A2 | 2-(Benz-)Imidazol-, 2-(Benz-)Oxazol- or 2-(Benz-)Thiazol-substituted Silanes | Wacker-Chemie GmbH (DE) | 2000-11-08 | — | — | EP | disclosed |