SCHEMBL388171

SCHEMBL388171

O=C1c2ccccc2CC1O

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ACHE P22303 6/20 0.59
METAP1 P53582 4/20 0.49
SMN1; SMN2 Q16637 1/20 0.46
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 1/20 0.45
MAPT P10636 1/20 0.45
KMT2A Q03164 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CYP19A1 P11511 1/20 0.45
TSHR P16473 1/20 0.44
CES1 P23141 1/20 0.41
MAOA P21397 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32679177 1.00 ACHE (0.59) ACHEMETAP1SMN1; SMN2KDM4EMEN1
SCHEMBL30737574 1.00 ACHE (0.59) ACHEMETAP1SMN1; SMN2KDM4EMEN1
SCHEMBL7998826 1.00 ACHE (0.59) ACHEMETAP1SMN1; SMN2KDM4EMEN1
SCHEMBL32679178 1.00 ACHE (0.59) ACHEMETAP1SMN1; SMN2KDM4EMEN1
SCHEMBL1093558 1.00 ACHE (0.59) ACHEMETAP1SMN1; SMN2KDM4EMEN1
SCHEMBL8077009 0.85 ACHE (0.45) ACHEMETAP1SMN1; SMN2KDM4EMEN1
SCHEMBL8077011 0.85 ACHE (0.45) ACHEMETAP1SMN1; SMN2KDM4EMEN1
SCHEMBL1094690 0.81 CYP19A1 (0.53) ACHESMN1; SMN2KDM4EMAPTCYP19A1
SCHEMBL30707960 0.81 CYP19A1 (0.53) ACHESMN1; SMN2KDM4EMAPTCYP19A1
SCHEMBL385513 0.81 CYP19A1 (0.53) ACHESMN1; SMN2KDM4EMAPTCYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117802632-A Special oiling agent for elasticized polyester FDY filaments and preparation method thereof 江苏恒科新材料有限公司 2024-04-02 CN claimed
CN-111171809-B Hydroxyl indenone derivative fluorescent probe and preparation method and application thereof 广州大学 2022-12-27 CN claimed
CN-108129306-B Synthesis method of 2-hydroxy-1-indanone compound 金华奥布朗医药科技有限公司 2021-04-06 CN claimed
CN-111171809-A Hydroxyl indenone derivative fluorescent probe and preparation method and application thereof 广州大学 2020-05-19 CN claimed
US-8153408-B2 Biocatalytic racemisation of alpha-hydroxyketones BASF SE (DE) 2012-04-10 US claimed
EP-1984515-B1 BIOCATALYTIC RACEMISATION OF ALPHA-HYDROXYKETONES BASF SE (DE) 2010-09-01 EP claimed
US-20090221046-A1 BIOCATALYTIC RACEMISATION OF ALPHA-HYDROXYKETONES BASF SE (DE) 2009-09-03 US claimed
EP-1984515-A1 BIOCATALYTIC RACEMISATION OF ALPHA-HYDROXYKETONES BASF SE (DE) 2008-10-29 EP claimed
EP-1432388-B1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL AG & CO KGAA (DE) 2008-06-18 EP claimed
WO-2007090767-A1 BIOCATALYTIC RACEMISATION OF ALPHA-HYDROXYKETONES BASF SE (DE) 2007-08-16 WO claimed
EP-1432428-B1 Agent for colouring fibres containing keratin HENKEL KGAA (DE) 2006-11-02 EP claimed
US-20050262647-A1 Agent for dyeing fibers containing keratin HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2005-12-01 US claimed
US-6057479-A MULTISTAGE REACTION OF HYDROXY INDANONE WITH AMINE TO FORM IMINE, HEATING AND HYDROGENATION NIPPON STEEL CHEMICAL CO., LTD. (JP) 2000-05-02 US claimed
EP-0874059-A1 PROCESSES FOR PRODUCING INDANE DERIVATIVES NIPPON STEEL CHEMICAL CO., LTD. (JP) 1998-10-28 EP claimed
EP-0874059-A2 PROCESSES FOR PRODUCING INDANE DERIVATIVES NIPPON STEEL CHEMICAL CO., LTD. (JP) 1998-10-28 EP claimed
US-3979320-A Liquid crystal composition HODOGAYA CHEMICAL CO., LTD. (JA) 1976-09-07 US claimed
US-3975285-A LONG LIFE DYNAMIC LIGHT SCATTERING PROPERTIES HODOGAYA CHEMICAL CO., LTD. (JA) 1976-08-17 US claimed
JP-10273474-A None JP disclosed
US-3979320-A Liquid crystal composition HODOGAYA CHEMICAL CO., LTD. (JA) 1976-09-07 US disclosed
US-3975285-A LONG LIFE DYNAMIC LIGHT SCATTERING PROPERTIES HODOGAYA CHEMICAL CO., LTD. (JA) 1976-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050262647-A1 Agent for dyeing fibers containing keratin KRT18, CKAP4, KRTCAP2 ACHE 1896/4885METAP1 3168/4885SMN1; SMN2 4730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.