Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | DNM2 | P50570 | 7/20 | 0.48 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8072012 | 0.97 | DNM2 (0.48) | KMT2ADNM2KCNH3SMN1; SMN2LMNA | |
| SCHEMBL8071819 | 0.93 | DNM2 (0.48) | KMT2ADNM2KCNH3SMN1; SMN2LMNA | |
| SCHEMBL8077182 | 0.93 | KMT2A (0.51) | KMT2ADNM2KCNH3SMN1; SMN2LMNA | |
| SCHEMBL24831501 | 0.90 | DNM2 (0.52) | KMT2ADNM2 | |
| SCHEMBL8077053 | 0.89 | SMN1; SMN2 (0.47) | KMT2ADNM2KCNH3SMN1; SMN2LMNA | |
| SCHEMBL22686843 | 0.89 | KMT2A (0.60) | KMT2ADNM2KCNH3SMN1; SMN2LMNA | |
| SCHEMBL20740715 | 0.89 | KMT2A (0.43) | KMT2ADNM2KCNH3SMN1; SMN2LMNA | |
| SCHEMBL18680416 | 0.87 | CXCR2 (0.40) | KMT2ADNM2KCNH3SMN1; SMN2LMNA | |
| SCHEMBL17563602 | 0.87 | CXCR2 (0.40) | KMT2ADNM2KCNH3SMN1; SMN2LMNA | |
| SCHEMBL8077213 | 0.86 | KMT2A (0.41) | KMT2ADNM2KCNH3SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648755-B1 | Improved process for the preparation of 2,4-di(alkylamino)-6-alkylthio-s-triazines and 2-alkylamino-4,6-di(alkylthio)-s-triazines | CIBA SC HOLDING AG (CH) | 2000-08-02 | — | — | EP | disclosed |
| US-5420274-A | Process for the preparation of 2,4-di(alkylamino)-6-alkylthio-s-triazines | CIBA-GEIGY CORPORATION (US) | 1995-05-30 | — | — | US | disclosed |
| EP-0648755-A1 | Improved process for the preparation of 2,4-Di(alkylamino)-6-alkylthio-s-triazines | CIBA-GEIGY AG (CH) | 1995-04-19 | — | — | EP | disclosed |