Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 8/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
| ▸ | BRS3 | P32247 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9493595 | 0.75 | HDAC3 (0.52) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL7786808 | 0.74 | HDAC3 (0.51) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9492798 | 0.74 | HDAC3 (0.51) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL18931339 | 0.73 | BRS3 (0.44) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL8987882 | 0.73 | HDAC3 (0.50) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9497689 | 0.73 | RARB (0.52) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL7790562 | 0.73 | RARB (0.52) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9497766 | 0.73 | RARB (0.52) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9496656 | 0.73 | RARB (0.52) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL7788958 | 0.73 | RARB (0.52) | HDAC3HDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755918-B1 | Photocrosslinkable liquid crystalline 1,2-phenylene derivatives | ROLIC AG (CH) | 2000-09-06 | — | — | EP | disclosed |
| EP-0755918-A2 | Photocrosslinkable liquid crystalline 1,2-phenylene derivatives | Rolic AG (CH) | 1997-01-29 | — | — | EP | disclosed |