Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83697 | 0.98 | TAAR1 (0.40) | TAAR1GPR84CYP19A1ACHEGAA | |
| SCHEMBL14088672 | 0.82 | CYP1A2 (0.44) | TAAR1GPR84CYP19A1GAAL3MBTL1 | |
| SCHEMBL12154323 | 0.82 | CYP19A1 (0.48) | TAAR1GPR84CYP19A1ACHEGAA | |
| SCHEMBL91867 | 0.82 | CYP19A1 (0.48) | TAAR1GPR84CYP19A1ACHEGAA | |
| SCHEMBL12219580 | 0.81 | CYP1A2 (0.45) | TAAR1GPR84CYP19A1GAAL3MBTL1 | |
| SCHEMBL84599 | 0.77 | KDM4E (0.38) | TAAR1GPR84CYP19A1ACHEGAA | |
| SCHEMBL84231 | 0.76 | TAAR1 (0.49) | TAAR1GPR84CYP19A1GAANPC1 | |
| SCHEMBL21524247 | 0.74 | CYP19A1 (0.46) | TAAR1GPR84CYP19A1GAAL3MBTL1 | |
| SCHEMBL21524299 | 0.73 | CYP19A1 (0.54) | GPR84CYP19A1GAAL3MBTL1KDM4E | |
| SCHEMBL21524253 | 0.71 | KDM4E (0.40) | GPR84CYP19A1GAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129002-B2 | Compounds for use in liquid crystal media | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |
| US-8129002-B2 | Compounds for use in liquid crystal media | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |
| US-7927671-B2 | Having two polymerizable groups at an end of a molecular long axis and one polymerizable group at an end of a molecular short axis; heat resistance, shrinkage, adhesive property, close adhesiveness, mechanical strength; liquid crystal display | CHISSO CORPORATION (JP) | 2011-04-19 | — | — | US | disclosed |
| US-7919648-B2 | Lateral α-substituted acrylate compound and polymer thereof | CHISSO CORPORATION (JP) | 2011-04-05 | — | — | US | disclosed |
| US-7785488-B2 | Lateral oxirane compound and polymer thereof | CHISSO CORPORATION (JP) | 2010-08-31 | — | — | US | disclosed |
| EP-1658350-B1 | COMPOUNDS FOR USE IN LIQUID CRYSTAL MEDIA | MERCK PATENT GMBH (DE) | 2010-01-20 | — | — | EP | disclosed |
| EP-1658351-B1 | MESOGENIC COMPOUNDS, MEDIUM FOR ELECTRO-OPTICAL DISPLAYS AND ELECTRO-OPTICAL DISPLAY | MERCK PATENT GMBH (DE) | 2009-10-28 | — | — | EP | disclosed |
| US-7531106-B2 | Mesogenic compounds, medium for electro-optical displays and electro-optical display | MERCK PATENT GMBH (DE) | 2009-05-12 | — | — | US | disclosed |
| US-7531106-B2 | Mesogenic compounds, medium for electro-optical displays and electro-optical display | MERCK PATENT GMBH (DE) | 2009-05-12 | — | — | US | disclosed |
| US-7440160-B2 | Electro-optical light modulating element, electro-optical display and modulating medium | MERCK PATENT GMBH (DE) | 2008-10-21 | — | — | US | disclosed |
| US-7440160-B2 | Electro-optical light modulating element, electro-optical display and modulating medium | MERCK PATENT GMBH (DE) | 2008-10-21 | — | — | US | disclosed |
| US-20080081133-A1 | Trifunctional compound, composition and polymer thereof | CHISSO CORPORATION | 2008-04-03 | — | — | US | disclosed |
| US-20070134447-A1 | Lateral a-substituted acrylate compound and polymer thereof | CHISSO CORPORATION | 2007-06-14 | — | — | US | disclosed |
| US-20070134440-A1 | Lateral oxirane compound and polymer thereof | CHISSO CORPORATION | 2007-06-14 | — | — | US | disclosed |
| EP-1561150-B1 | ELECTROOPTICAL LIGHT MODULATING ELEMENT, ELECTROOPTICAL DISPLAY AND MODULATING MEDIUM | MERCK PATENT GMBH (DE) | 2007-01-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081133-A1 | Trifunctional compound, composition and polymer thereof | OXER1, AFF1, OXGR1 | TAAR1 1219/4885GPR84 2689/4885CYP19A1 452/4885 |
| US-20070134447-A1 | Lateral a-substituted acrylate compound and polymer thereof | AFF1, CNKSR1, LEF1 | TAAR1 1682/4885GPR84 3635/4885CYP19A1 2001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.