SCHEMBL91867

SCHEMBL91867

CC1CCC(C2COc3ccc4ccccc4c3-c3c(ccc4ccccc34)OC2)CC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.48
GAA P10253 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ALDH1A1 P00352 2/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
GPR84 Q9NQS5 1/20 0.39
MAPT P10636 2/20 0.36
TAAR1 Q96RJ0 1/20 0.36
KDM4E B2RXH2 1/20 0.36
ACHE P22303 1/20 0.35
HTR1A P08908 1/20 0.34
HTR7 P34969 1/20 0.34
HTR2B P41595 1/20 0.34
TMEM97 Q5BJF2 1/20 0.34
SIGMAR1 Q99720 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12154323 1.00 CYP19A1 (0.48) CYP19A1GAAL3MBTL1ALDH1A1CYP3A4
SCHEMBL21524299 0.92 CYP19A1 (0.54) CYP19A1GAAL3MBTL1ALDH1A1CYP3A4
SCHEMBL21524247 0.92 CYP19A1 (0.46) CYP19A1GAAL3MBTL1ALDH1A1CYP3A4
SCHEMBL21524292 0.88 CYP19A1 (0.50) CYP19A1GAAL3MBTL1ALDH1A1CYP3A4
SCHEMBL18385881 0.88 CYP19A1 (0.54) CYP19A1GAAL3MBTL1ALDH1A1CYP3A4
SCHEMBL21524246 0.86 CYP19A1 (0.55) CYP19A1GAAL3MBTL1ALDH1A1CYP3A4
SCHEMBL21524240 0.86 CYP19A1 (0.55) CYP19A1GAAL3MBTL1ALDH1A1CYP3A4
SCHEMBL15615789 0.85 CYP19A1 (0.54) CYP19A1GAAL3MBTL1ALDH1A1CYP3A4
SCHEMBL20172061 0.85 CYP19A1 (0.45) CYP19A1GAAL3MBTL1ALDH1A1CYP3A4
SCHEMBL10035139 0.84 CYP19A1 (0.55) CYP19A1GAAL3MBTL1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228879-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE THEREOF JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2024-07-11 US disclosed
US-20240026223-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING SAME JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2024-01-25 US disclosed
US-11795398-B2 Liquid-crystalline medium and liquid-crystal display comprising the same and compounds MERCK PATENT GMBH (DE) 2023-10-24 US disclosed
US-11796856-B1 Organic solid crystals having helical structures formed using cholesteric liquid crystals META PLATFORMS TECHNOLOGIES, LLC (US) 2023-10-24 US disclosed
US-11788010-B2 Liquid crystal composition and liquid crystal display device comprising the same JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-10-17 US disclosed
US-11667841-B2 Dibenzofuran and dibenzothiophene derivatives MERCK PATENT GMBH (DE) 2023-06-06 US disclosed
US-20230159826-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING THE SAME JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-05-25 US disclosed
WO-2023071657-A1 LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION THEREOF, AND LIQUID CRYSTAL DISPLAY DEVICE 江苏和成显示科技有限公司 2023-05-04 WO disclosed
US-20230045269-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2023-02-09 US disclosed
US-11447701-B2 Liquid-crystalline medium and liquid-crystal display comprising the same and compounds MERCK PATENT GMBH (DE) 2022-09-20 US disclosed
US-8129002-B2 Compounds for use in liquid crystal media MERCK PATENT GMBH (DE) 2012-03-06 US disclosed
US-8129002-B2 Compounds for use in liquid crystal media MERCK PATENT GMBH (DE) 2012-03-06 US disclosed
EP-1658350-B1 COMPOUNDS FOR USE IN LIQUID CRYSTAL MEDIA MERCK PATENT GMBH (DE) 2010-01-20 EP disclosed
EP-1658351-B1 MESOGENIC COMPOUNDS, MEDIUM FOR ELECTRO-OPTICAL DISPLAYS AND ELECTRO-OPTICAL DISPLAY MERCK PATENT GMBH (DE) 2009-10-28 EP disclosed
US-7531106-B2 Mesogenic compounds, medium for electro-optical displays and electro-optical display MERCK PATENT GMBH (DE) 2009-05-12 US disclosed
US-7531106-B2 Mesogenic compounds, medium for electro-optical displays and electro-optical display MERCK PATENT GMBH (DE) 2009-05-12 US disclosed
US-7440160-B2 Electro-optical light modulating element, electro-optical display and modulating medium MERCK PATENT GMBH (DE) 2008-10-21 US disclosed
US-7440160-B2 Electro-optical light modulating element, electro-optical display and modulating medium MERCK PATENT GMBH (DE) 2008-10-21 US disclosed
US-7419706-B2 Liquid crystalline medium MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2008-09-02 US disclosed
EP-1561150-B1 ELECTROOPTICAL LIGHT MODULATING ELEMENT, ELECTROOPTICAL DISPLAY AND MODULATING MEDIUM MERCK PATENT GMBH (DE) 2007-01-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667841-B2 Dibenzofuran and dibenzothiophene derivatives DDT, MYT1, DBF4 CYP19A1 343/4885GAA 3363/4885L3MBTL1 408/4885
US-11447701-B2 Liquid-crystalline medium and liquid-crystal display comprising the same and compounds NEFM, FES, SBDS CYP19A1 3320/4885GAA 3705/4885L3MBTL1 2135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.