Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 5/20 | 0.42 |
| ▸ | MMP2 | P08253 | 5/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8075509 | 1.00 | HDAC1 (0.44) | HDAC1HDAC2MMP3MMP2PTGER1 | |
| SCHEMBL8082122 | 1.00 | HDAC1 (0.44) | HDAC1HDAC2MMP3MMP2PTGER1 | |
| SCHEMBL8082015 | 1.00 | HDAC1 (0.44) | HDAC1HDAC2MMP3MMP2PTGER1 | |
| SCHEMBL8067477 | 1.00 | HDAC1 (0.44) | HDAC1HDAC2MMP3MMP2PTGER1 | |
| SCHEMBL8076445 | 1.00 | HDAC1 (0.44) | HDAC1HDAC2MMP3MMP2PTGER1 | |
| SCHEMBL8067411 | 1.00 | HDAC1 (0.44) | HDAC1HDAC2MMP3MMP2PTGER1 | |
| SCHEMBL8082135 | 1.00 | HDAC1 (0.44) | HDAC1HDAC2MMP3MMP2PTGER1 | |
| SCHEMBL8080509 | 0.99 | MMP3 (0.43) | HDAC1HDAC2MMP3MMP2PTGER1 | |
| SCHEMBL8081949 | 0.97 | MMP2 (0.42) | HDAC1HDAC2MMP3MMP2PTGER1 | |
| SCHEMBL8080446 | 0.91 | KDM4E (0.45) | HDAC1HDAC2MMP3MMP2PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755918-B1 | Photocrosslinkable liquid crystalline 1,2-phenylene derivatives | ROLIC AG (CH) | 2000-09-06 | — | — | EP | disclosed |
| EP-0755918-A2 | Photocrosslinkable liquid crystalline 1,2-phenylene derivatives | Rolic AG (CH) | 1997-01-29 | — | — | EP | disclosed |