Biphenyl

Biphenyl

SCHEMBL8077261

CC(=O)CC(=O)O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.52
MAPT P10636 3/20 0.52
RECQL P46063 1/20 0.52
LMNA P02545 2/20 0.50
GAA P10253 2/20 0.50
MMP12 P39900 2/20 0.50
ABCC4 O15439 1/20 0.50
TSHR P16473 1/20 0.50
PTGS1 P23219 1/20 0.50
HTT P42858 1/20 0.50
KDM4E B2RXH2 1/20 0.47
APOBEC3A P31941 1/20 0.47
GFER P55789 1/20 0.47
HDAC1 Q13547 1/20 0.47
APOBEC3G Q9HC16 1/20 0.47
FFAR1 O14842 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
CYP1A2 P05177 2/20 0.45
RAB9A P51151 2/20 0.45
CYP2D6 P10635 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL27519918 1.00 SMN1; SMN2 (0.52) SMN1; SMN2MAPTRECQLLMNAGAA
Acetoacetic Acid SCHEMBL3227038 0.90 SMN1; SMN2 (0.46) SMN1; SMN2MAPTRECQLLMNAGAA
Biphenyl SCHEMBL27660096 0.90 MAPT (0.56) SMN1; SMN2MAPTRECQLLMNAGAA
Acetoacetic Acid SCHEMBL28147867 0.88 MAPT (0.74) SMN1; SMN2MAPTLMNAKDM4EFFAR1
Biphenyl SCHEMBL6525433 0.85 LMNA (0.58) SMN1; SMN2MAPTRECQLLMNAGAA
Biphenyl SCHEMBL1029706 0.85 LMNA (0.58) SMN1; SMN2MAPTRECQLLMNAGAA
Acetoacetic Acid SCHEMBL28221327 0.84 KDM4E (0.50) MAPTRECQLLMNAGAAHTT
Acetoacetic Acid SCHEMBL9704495 0.84 NPC1 (0.50) SMN1; SMN2MAPTRECQLLMNATSHR
Acetoacetic Acid SCHEMBL28140837 0.84 NPC1 (0.50) SMN1; SMN2MAPTRECQLLMNATSHR
Acetoacetic Acid SCHEMBL9501475 0.82 TSHR (0.48) SMN1; SMN2MAPTRECQLLMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115232192-B Azo type hypoxic response type dipeptide supramolecular monomer and preparation method and application thereof 济宁医学院 2023-03-28 CN claimed
EP-0637613-B1 RESIN COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2000-10-25 EP disclosed
US-5543474-A BLEND OF A AROMATIC POLYAMIDEIMIDE COPOLYMER AND A POLYESTER MITSUBISHI GAS COMPANY, INC. (JP) 1996-08-06 US disclosed
EP-0637613-A1 RESIN COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1995-02-08 EP disclosed