Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
| ▸ | GPR88 | Q9GZN0 | 3/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 4/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8063894 | 0.86 | C5AR1 (0.39) | MCL1BCL2A1GPR88PTGER1PTGER4 | |
| SCHEMBL7734901 | 0.86 | THRA (0.50) | MCL1BCL2A1SCN9AGPR88MMP3 | |
| SCHEMBL7735851 | 0.84 | THRA (0.42) | MCL1BCL2A1SCN9AGPR88MMP3 | |
| SCHEMBL7725082 | 0.76 | THRA (0.53) | MCL1BCL2A1SCN9AC5AR1THRA | |
| SCHEMBL7725103 | 0.74 | THRA (0.44) | MCL1BCL2A1SCN9AC5AR1THRA | |
| SCHEMBL3895970 | 0.73 | SCN9A (0.39) | SCN9AC5AR1 | |
| SCHEMBL7725137 | 0.71 | THRA (0.52) | MCL1BCL2A1GPR88C5AR1THRA | |
| SCHEMBL3882367 | 0.71 | FABP4 (0.44) | GPR88PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3892394 | 0.71 | AKR1C3 (0.38) | GPR88PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL7735782 | 0.70 | THRA (0.43) | MCL1BCL2A1GPR88C5AR1THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1024130-A1 | BIPHENYL-5-ALKANOIC ACID DERIVATIVES AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-08-02 | — | — | EP | disclosed |