Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 15/20 | 0.35 |
| ▸ | MAOA | P21397 | 15/20 | 0.35 |
| ▸ | MAOB | P27338 | 15/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.31 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.31 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4331945 | 0.82 | ADORA3 (0.32) | KDM1AMAOAMAOBADORA3HTR2A | |
| SCHEMBL20456224 | 0.80 | KDM1A (0.46) | KDM1AMAOAMAOBHTR2AHTR2C | |
| SCHEMBL8077336 | 0.77 | KDM1A (0.38) | KDM1AMAOAMAOBHTR2AHTR2C | |
| SCHEMBL21043746 | 0.76 | MAPT (0.40) | KDM1AADORA3CACNA1FCACNA1DCACNA1S | |
| Propane SCHEMBL23045273 | 0.74 | KDM1A (0.43) | KDM1AMAOAMAOBHTR2AHTR2C | |
| SCHEMBL1074533 | 0.73 | KDM1A (0.40) | KDM1AMAOAMAOBHTR2AHTR2C | |
| SCHEMBL5185255 | 0.72 | POLB (0.34) | KDM1AMAOAMAOB | |
| Methane SCHEMBL16507862 | 0.71 | KDM1A (0.39) | KDM1AMAOAMAOBHTR2AHTR2C | |
| SCHEMBL10715859 | 0.70 | HTR2A (0.33) | HTR2AHTR2CHTR2B | |
| Ether SCHEMBL14674326 | 0.70 | KDM1A (0.37) | KDM1AMAOAMAOBADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995004072-A1 | PEPTOID ALPHA-1 ADRENERGIC RECEPTOR LIGANDS | CHIRON CORPORATION (US) | 1995-02-09 | — | — | WO | disclosed |