Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | GNG2 | P59768 | 4/20 | 0.36 |
| ▸ | GNB1 | P62873 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP3 | P08254 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | MMP12 | P39900 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | MMP14 | P50281 | 2/20 | 0.33 |
| ▸ | MMP16 | P51512 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8432810 | 0.82 | TTR (0.47) | TTRGNG2GNB1CYP1A2AURKA | |
| SCHEMBL9768531 | 0.82 | MYC (0.44) | TTRCA1CA2SLC6A2SLC6A4 | |
| SCHEMBL31504545 | 0.82 | TTR (0.47) | TTRGNG2GNB1CYP1A2AURKA | |
| SCHEMBL6275541 | 0.80 | TTR (0.50) | TTRCYP1A2CA2AURKAAURKB | |
| SCHEMBL15465886 | 0.78 | TTR (0.43) | TTRCYP1A2AURKAAURKBALDH1A1 | |
| SCHEMBL28538022 | 0.77 | TTR (0.42) | TTRCA1CA2ALDH1A1LMNA | |
| SCHEMBL29085257 | 0.76 | TTR (0.44) | TTRGNG2GNB1CYP1A2CA1 | |
| SCHEMBL15464816 | 0.75 | TTR (0.41) | TTRCA2AURKAAURKBMMP2 | |
| SCHEMBL599747 | 0.75 | TTR (0.59) | TTRCYP1A2CA1CA2AURKA | |
| SCHEMBL4360942 | 0.73 | GABRA1 (0.43) | TTRGNG2GNB1CYP1A2AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027387-A1 | DOUBLE REACTIVE DYES | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999023169-A1 | DOUBLE REACTIVE DYES | BASF AKTIENGESELLSCHAFT (DE) | 1999-05-14 | — | — | WO | disclosed |