Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 5/20 | 0.39 |
| ▸ | MMP2 | P08253 | 5/20 | 0.39 |
| ▸ | MMP3 | P08254 | 5/20 | 0.39 |
| ▸ | MMP9 | P14780 | 5/20 | 0.39 |
| ▸ | MMP8 | P22894 | 5/20 | 0.39 |
| ▸ | MMP12 | P39900 | 5/20 | 0.39 |
| ▸ | MMP13 | P45452 | 5/20 | 0.39 |
| ▸ | MMP14 | P50281 | 5/20 | 0.39 |
| ▸ | MMP16 | P51512 | 5/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8339184 | 0.82 | ADRA1D (0.43) | MMP1MMP2MMP3MMP9MMP8 | |
| SCHEMBL8077339 | 0.82 | TTR (0.42) | MYCMMP1MMP2MMP3MMP9 | |
| SCHEMBL6275541 | 0.82 | TTR (0.50) | CA2CYP3A4IFNAR1LMNATDP1 | |
| Water SCHEMBL29718461 | 0.82 | CTSB (0.50) | MYCLMNATTR | |
| SCHEMBL8719378 | 0.81 | HIF1A (0.46) | MYCSLC6A4SLC6A2SLC6A3CA1 | |
| SCHEMBL14991455 | 0.81 | MYC (0.47) | MYCMMP1MMP2MMP3MMP9 | |
| SCHEMBL31425768 | 0.81 | MYC (0.47) | MYCMMP1MMP2MMP3MMP9 | |
| SCHEMBL31425767 | 0.81 | MYC (0.47) | MYCMMP1MMP2MMP3MMP9 | |
| SCHEMBL9769575 | 0.81 | MAPT (0.42) | MYCMMP1MMP2MMP3MMP9 | |
| SCHEMBL3363314 | 0.81 | CA2 (0.49) | SLC6A4SLC6A2SLC6A3CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190753-A1 | Methods and Compositions for Treating Amyloid-Related Diseases | BELLUS HEALTH (INTERNATIONAL) LIMITED (CH) | 2010-07-29 | — | — | US | disclosed |
| US-7598269-B2 | Methods and compositions for treating amyloid-related diseases | BELLUS HEALTH (INTERNATIONAL) LIMITED (CH) | 2009-10-06 | — | — | US | disclosed |
| US-20080015180-A1 | Methods and compositions for treating amyloid-related diseases | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2008-01-17 | — | — | US | disclosed |
| US-7244764-B2 | Methods and compositions for treating amyloid-related diseases | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2007-07-17 | — | — | US | disclosed |
| US-7244764-B2 | Methods and compositions for treating amyloid-related diseases | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2007-07-17 | — | — | US | disclosed |
| US-5053494-A | FIBER REACTIVE POLYAZO DYE HAVING TWO VINYLSULFONE TYPE REACTIVE GROUPS THROUGH TRIAZINYL BRIDGING GROUP | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-10-01 | — | — | US | disclosed |
| EP-0266774-B1 | POLYAZO COMPOUND HAVING TWO VINYLSULFONE TYPE FIBER REACTIVE GROUPS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| EP-0266774-A1 | Polyazo compound having two vinylsulfone type fiber reactive groups | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-05-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190753-A1 | Methods and Compositions for Treating Amyloid-Related Diseases | APP, PSEN1, PSEN2 | MYC 3501/4885MMP1 903/4885MMP2 1137/4885 |
| US-20080015180-A1 | Methods and compositions for treating amyloid-related diseases | APP, PSEN1, PSEN2 | MYC 3501/4885MMP1 903/4885MMP2 1137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.