Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8075773 | 0.86 | OPRK1 (0.46) | UTS2ROPRM1 | |
| SCHEMBL8080511 | 0.84 | AOC3 (0.54) | ACHEUTS2ROPRM1TMEM97SIGMAR1 | |
| SCHEMBL5102674 | 0.79 | UGT2B7 (0.50) | UTS2RSIGMAR1 | |
| SCHEMBL14578374 | 0.74 | CARM1 (0.60) | SIGMAR1CARM1PRMT6PRMT8 | |
| SCHEMBL2888672 | 0.74 | AOC3 (0.48) | UTS2R | |
| SCHEMBL13025061 | 0.74 | AOC3 (0.48) | UTS2R | |
| SCHEMBL8060864 | 0.74 | AOC3 (0.48) | UTS2R | |
| SCHEMBL8082126 | 0.73 | AOC3 (0.47) | UTS2RSIGMAR1 | |
| SCHEMBL11051116 | 0.73 | UGT2B7 (0.55) | — | |
| SCHEMBL8297797 | 0.73 | HTR2A (0.62) | SIGMAR1CARM1PRMT6PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051661-A2 | SUBSTITUTED ARYL ALKYLAMINO-OXY-ANALOGS AND USES THEREOF | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2009-04-23 | — | — | WO | disclosed |