⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8077536 | 0.84 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL8079080 | 0.73 | LMNA (0.55) | — | |
| SCHEMBL8069905 | 0.72 | LMNA (0.43) | — | |
| SCHEMBL9410418 | 0.69 | CYP2C9 (0.40) | — | |
| SCHEMBL7996873 | 0.69 | POLB (0.50) | — | |
| SCHEMBL9410387 | 0.68 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL9410490 | 0.66 | SCN3A (0.36) | — | |
| SCHEMBL8081895 | 0.62 | LMNA (0.55) | — | |
| SCHEMBL8079088 | 0.62 | LMNA (0.48) | — | |
| SCHEMBL8079173 | 0.62 | LMNA (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634403-B1 | N-polyhalobenzyl-pyrazole carboxamides endowed with acaricidal and insecticidal activity | ISAGRO SPA (IT) | 2000-09-13 | — | — | EP | disclosed |
| US-5541214-A | N-polyhalobenzyl-pyrazole carboxamides endowed with acaricidal and insecticidal activity | ISAGRO S.P.A. (IT) | 1996-07-30 | — | — | US | disclosed |
| EP-0634403-A1 | N-polyhalobenzyl-pyrazole carboxamides endowed with acaricidal and insecticidal activity | ISAGRO S.p.A. (IT) | 1995-01-18 | — | — | EP | disclosed |