Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 5/20 | 0.35 |
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976279 | 0.89 | ALDH1A1 (0.40) | HTTKDM4EPOLBSMN1; SMN2CYP1A2 | |
| SCHEMBL4045393 | 0.86 | CA12 (0.45) | HTTDRD2CYP2D6TDP1CYP2C19 | |
| SCHEMBL7976286 | 0.86 | HTT (0.40) | HTTKDM4EPOLBSMN1; SMN2CYP1A2 | |
| SCHEMBL8060882 | 0.83 | RAB9A (0.50) | HTTPOLBSMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL7979325 | 0.82 | HTT (0.40) | HTTKDM4ESMN1; SMN2NPSR1CYP1A2 | |
| SCHEMBL7965715 | 0.81 | KDM4E (0.41) | HTTKDM4EPOLBSMN1; SMN2CYP1A2 | |
| SCHEMBL8065554 | 0.81 | HTT (0.36) | HTTKDM4ESMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL8075519 | 0.80 | NPC1 (0.49) | POLBSMN1; SMN2RECQLALDH1A1TDP1 | |
| SCHEMBL8060900 | 0.80 | HPGD (0.40) | HTTPOLBCYP1A2ALDH1A1CYP2C19 | |
| SCHEMBL7979456 | 0.80 | CYP1A2 (0.39) | HTTKDM4ESMN1; SMN2CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824514-B1 | DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2000-09-06 | — | — | EP | disclosed |