Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 3/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15467500 | 0.90 | P2RX7 (0.37) | CYP11B2CYP11B1CYP17A1GABRA1GABRG2 | |
| SCHEMBL807456 | 0.75 | MAPT (0.36) | CYP11B2CYP11B1CYP17A1MAPT | |
| SCHEMBL794339 | 0.70 | CYP17A1 (0.37) | CYP17A1CYP1A2MAPT | |
| SCHEMBL793782 | 0.69 | CDC7 (0.40) | CYP11B2CYP11B1CYP17A1 | |
| SCHEMBL10286704 | 0.69 | CYP11B2 (0.38) | CYP11B2CYP11B1CYP17A1MAPT | |
| SCHEMBL807907 | 0.68 | CYP11B2 (0.43) | CYP11B2CYP11B1CYP17A1CYP1A2GABRA1 | |
| SCHEMBL807995 | 0.68 | CYP11B2 (0.42) | CYP11B2CYP11B1MAPT | |
| SCHEMBL798823 | 0.67 | CYP17A1 (0.52) | CYP17A1MAPT | |
| SCHEMBL798870 | 0.66 | CYP11B2 (0.47) | CYP11B2CYP11B1CYP17A1CYP1A2 | |
| SCHEMBL793874 | 0.66 | CHRM1 (0.41) | CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035078-A1 | 17α-HYDROXYLASE/C17,20-LYASE INHIBITORS | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |