SCHEMBL8077665

SCHEMBL8077665

Cc1ccc(-c2nc(-c3ccccc3)c3ccccc3n2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.71
▸ KMT2A Q03164 3/20 0.71
▸ ATM Q13315 2/20 0.71
▸ ALDH1A1 P00352 3/20 0.66
▸ ADORA2A P29274 3/20 0.66
▸ KDM4E B2RXH2 2/20 0.66
▸ CYP1A1 P04798 1/20 0.64
▸ CYP1A2 P05177 1/20 0.64
▸ CYP1B1 Q16678 1/20 0.64
▸ TDP1 Q9NUW8 1/20 0.62
▸ NPC1 O15118 1/20 0.60
▸ XBP1 P17861 1/20 0.60
▸ HTT P42858 1/20 0.60
▸ RAB9A P51151 1/20 0.60
▸ NPSR1 Q6W5P4 1/20 0.60
▸ LMNA P02545 1/20 0.59
▸ TP53 P04637 1/20 0.59
▸ MAPT P10636 1/20 0.59
▸ ABCG2 Q9UNQ0 1/20 0.59
▸ DPP4 P27487 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10940161 1.00 MEN1 (0.71) MEN1KMT2AATMALDH1A1ADORA2A
SCHEMBL12655059 0.98 MEN1 (0.69) MEN1KMT2AATMALDH1A1ADORA2A
SCHEMBL24689824 0.92 MEN1 (0.61) MEN1KMT2AATMALDH1A1ADORA2A
SCHEMBL24689766 0.91 MEN1 (0.64) MEN1KMT2AATMALDH1A1ADORA2A
SCHEMBL16436798 0.89 MEN1 (0.86) MEN1KMT2AATMALDH1A1ADORA2A
SCHEMBL22483256 0.89 MEN1 (0.80) MEN1KMT2AATMALDH1A1ADORA2A
SCHEMBL22058673 0.89 MEN1 (0.80) MEN1KMT2AATMALDH1A1ADORA2A
SCHEMBL23606297 0.89 MEN1 (0.86) MEN1KMT2AATMALDH1A1ADORA2A
SCHEMBL4393626 0.89 MEN1 (0.79) MEN1KMT2AATMALDH1A1ADORA2A
SCHEMBL30484133 0.89 MEN1 (0.79) MEN1KMT2AATMALDH1A1ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11793073-B2 Host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-17 — — US disclosed
US-11793073-B2 Host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-17 — — US disclosed
EP-3356369-B1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING TRIAZINE GROUPS FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO (JP) 2022-05-04 — — EP disclosed
US-20210376256-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-12-02 — — US disclosed
US-11127905-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-09-21 — — US disclosed
EP-3356368-B1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLYL GROUPS, CARBAZOLYL GROUPS, BENZOFURANE GROUPS OR BENZOTHIOPHENE GROUPS FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO (JP) 2021-07-21 — — EP disclosed
EP-3150604-B1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLYLYL GROUPS, CARBAZOLYL GROUPS, BENZOFURANE GROUPS OR BENZOTHIOPHENE GROUPS FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO (JP) 2021-07-14 — — EP disclosed
EP-3257093-B1 ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS MERCK PATENT GMBH (DE) 2021-07-07 — — EP disclosed
CN-106632086-B 2- (2- iodo aryl) quinazoline compounds and preparation method thereof 江西省林业科学院 2019-08-09 — — CN disclosed
US-10249831-B2 Electronic device containing cyclic lactams MERCK PATENT GMBH (DE) 2019-04-02 — — US disclosed
CN-106632086-A 2-(2-iodoaryl)quinazoline compound and preparation method thereof 江西省林业科学院 2017-05-10 — — CN disclosed
EP-3150604-A1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLYL GROUPS, CARBAZOLYL GROUPS, BENZOFURANE GROUPS OR BENZOTHIOPHENE GROUPS FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO., LTD. (JP) 2017-04-05 — — EP disclosed
US-20170033295-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-02-02 — — US disclosed
US-20170033295-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-02-02 — — US disclosed
WO-2016198144-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2016-12-15 — — WO disclosed
US-20150060833-A1 MATERIAL FOR ORGANIC ELECTRONIC DEVICE, AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2015-03-05 — — US disclosed
US-20150060833-A1 MATERIAL FOR ORGANIC ELECTRONIC DEVICE, AND ORGANIC ELECTRONIC DEVICE USING THE SAME LG CHEM, LTD. (KR) 2015-03-05 — — US disclosed
EP-0655456-B1 PHOSPHONIC DIESTER DERIVATIVE OTSUKA PHARMA CO LTD (JP) 2000-09-06 — — EP disclosed
US-5624918-A Phosphonic diester derivatives OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1997-04-29 — — US disclosed
EP-0655456-A1 PHOSPHONIC DIESTER DERIVATIVE OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1995-05-31 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10249831-B2 Electronic device containing cyclic lactams OXA1L, UROD, MRPL21 MEN1 2450/4885KMT2A 3341/4885ATM 3206/4885
US-11793073-B2 Host materials for electroluminescent devices MCM6, MCM2, MCM4 MEN1 438/4885KMT2A 3882/4885ATM 3893/4885
US-20170033295-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP MEN1 4546/4885KMT2A 3013/4885ATM 4394/4885
US-20210376256-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP MEN1 4546/4885KMT2A 3013/4885ATM 4394/4885
US-11127905-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, OSBP MEN1 4546/4885KMT2A 3013/4885ATM 4394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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