Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 9/20 | 1.00 |
| ▸ | CYP19A1 | P11511 | 9/20 | 1.00 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8075850 | 0.83 | CYP19A1 (1.00) | CYP17A1CYP19A1HSD11B1MEN1KMT2A | |
| SCHEMBL1733254 | 0.83 | CYP17A1 (0.73) | CYP17A1CYP19A1HSD11B1P2RX7ALDH1A1 | |
| SCHEMBL3321259 | 0.82 | HSD11B1 (1.00) | CYP17A1CYP19A1HSD11B1MEN1KMT2A | |
| Trimethylammonium SCHEMBL7978797 | 0.78 | CYP17A1 (0.66) | CYP17A1CYP19A1HSD11B1MEN1KMT2A | |
| SCHEMBL1770008 | 0.77 | HSD11B1 (0.67) | CYP17A1CYP19A1HSD11B1MEN1KMT2A | |
| SCHEMBL31613300 | 0.76 | CYP17A1 (0.63) | CYP17A1CYP19A1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL21082070 | 0.76 | CYP17A1 (0.61) | CYP17A1CYP19A1HSD11B1MEN1KMT2A | |
| SCHEMBL13333015 | 0.76 | CYP17A1 (1.00) | CYP17A1CYP19A1HSD11B1MEN1KMT2A | |
| SCHEMBL31538453 | 0.75 | CYP17A1 (0.66) | CYP17A1CYP19A1MEN1KMT2AP2RX7 | |
| SCHEMBL20620855 | 0.75 | CYP17A1 (0.60) | CYP17A1CYP19A1HSD11B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640072-B1 | Derivatives of pyridine as hydroxylase and lyase inhibitors | BTG INT LTD (GB) | 2000-08-23 | — | — | EP | disclosed |
| US-5595995-A | ANTICARCINOGENIC AGENTS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1997-01-21 | — | — | US | disclosed |