Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.53 |
| ▸ | PPARA | Q07869 | 3/20 | 0.53 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | PPIB | P23284 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13110980 | 0.83 | HDAC1 (0.58) | — | |
| SCHEMBL8093782 | 0.82 | HDAC1 (0.49) | UTS2RMEN1KMT2A | |
| SCHEMBL13111067 | 0.82 | HDAC1 (0.47) | UTS2R | |
| SCHEMBL27545775 | 0.79 | CYP2D6 (0.50) | PPARGPPARAUTS2RCYP19A1CNR2 | |
| SCHEMBL14065145 | 0.76 | UTS2R (0.60) | PPARGPPARAUTS2RCYP19A1MEN1 | |
| SCHEMBL14065176 | 0.75 | UTS2R (0.84) | PPARGPPARAUTS2RCYP19A1 | |
| SCHEMBL14064826 | 0.73 | UTS2R (0.66) | PPARGPPARAUTS2RCYP19A1 | |
| SCHEMBL22813473 | 0.73 | ADRB1 (0.49) | — | |
| SCHEMBL28552915 | 0.73 | ADRB1 (0.49) | — | |
| SCHEMBL14065228 | 0.72 | UTS2R (0.68) | PPARGPPARAUTS2RCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009015237-A1 | NOVEL COMPOUNDS AND METHODS OF USING THEM | SYNDAX PHARMACEUTICALS, INC. (US) | 2009-01-29 | — | — | WO | disclosed |