Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.68 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 3/20 | 0.44 |
| ▸ | HTR2B | P41595 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8085018 | 0.88 | CNR2 (0.54) | CNR2GPR84MEN1KMT2AHTR2A | |
| SCHEMBL4409616 | 0.81 | CNR2 (1.00) | CNR2MEN1KMT2A | |
| SCHEMBL4405919 | 0.75 | CNR2 (0.80) | CNR2MEN1KMT2AHTR2C | |
| SCHEMBL4405983 | 0.74 | CNR2 (1.00) | CNR2 | |
| SCHEMBL9666604 | 0.73 | MEN1 (0.61) | MEN1KMT2AHTR1A | |
| SCHEMBL8091141 | 0.73 | CNR2 (0.62) | CNR2MEN1KMT2A | |
| SCHEMBL8089406 | 0.73 | CNR2 (0.70) | CNR2MEN1KMT2AHTR2C | |
| SCHEMBL4551332 | 0.72 | CNR2 (0.89) | CNR2HTR2C | |
| SCHEMBL4409562 | 0.72 | CNR2 (0.84) | CNR2MEN1KMT2A | |
| SCHEMBL4418089 | 0.71 | CNR2 (0.82) | CNR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017919-A | Compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0887340-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 1998-12-30 | — | — | EP | disclosed |