Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | ME2 | P23368 | 1/20 | 0.42 |
| ▸ | ME1 | P48163 | 1/20 | 0.42 |
| ▸ | ME3 | Q16798 | 1/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8085081 | 0.80 | CNR2 (0.62) | CNR2MEN1NPC1ALDH1A1GAA | |
| SCHEMBL4551332 | 0.78 | CNR2 (0.89) | CNR2ALDH1A1NR5A1 | |
| SCHEMBL8085031 | 0.77 | CNR2 (0.56) | CNR2ALDH1A1GAAKMT2A | |
| SCHEMBL8089406 | 0.77 | CNR2 (0.70) | CNR2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL4405983 | 0.76 | CNR2 (1.00) | CNR2 | |
| SCHEMBL6536140 | 0.76 | NR5A1 (0.52) | CNR2MEN1NPC1ALDH1A1GAA | |
| SCHEMBL2499130 | 0.75 | GRM5 (0.46) | CNR2MEN1NPC1ALDH1A1GAA | |
| SCHEMBL6183029 | 0.73 | ITGB3 (0.41) | CNR2MEN1NPC1ALDH1A1GAA | |
| SCHEMBL4405919 | 0.73 | CNR2 (0.80) | CNR2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL31409495 | 0.73 | PARP1 (0.50) | CNR2ALDH1A1GAAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017919-A | Compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0887340-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 1998-12-30 | — | — | EP | disclosed |