Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4551332 | 0.86 | CNR2 (0.89) | CNR2LMNAALDH1A1KDM4EESR1 | |
| SCHEMBL8085031 | 0.83 | CNR2 (0.56) | CNR2KMT2AHTTLMNAALDH1A1 | |
| SCHEMBL4405983 | 0.82 | CNR2 (1.00) | CNR2 | |
| SCHEMBL8078040 | 0.78 | CNR2 (0.69) | CNR2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL8085883 | 0.77 | CNR2 (0.47) | CNR2LMNAALDH1A1S1PR5KDM4E | |
| SCHEMBL14201244 | 0.77 | CNR2 (0.83) | CNR2MAPTMEN1KMT2AHTT | |
| SCHEMBL8091141 | 0.77 | CNR2 (0.62) | CNR2MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL4410691 | 0.76 | CNR2 (1.00) | CNR2MAPTMEN1KMT2ALMNA | |
| SCHEMBL4416446 | 0.75 | CNR2 (0.73) | CNR2MEN1KMT2AHTTPOLB | |
| SCHEMBL4405919 | 0.75 | CNR2 (0.80) | CNR2MAPTMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017919-A | Compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0887340-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 1998-12-30 | — | — | EP | disclosed |