Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | WNT3A | P56704 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10600889 | 1.00 | GAA (0.67) | GAATDP1L3MBTL1HDAC8HDAC1 | |
| SCHEMBL10599678 | 1.00 | GAA (0.67) | GAATDP1L3MBTL1HDAC8HDAC1 | |
| SCHEMBL7898046 | 0.87 | GAA (0.54) | GAATDP1L3MBTL1HDAC8HDAC1 | |
| SCHEMBL14261447 | 0.87 | GAA (0.54) | GAATDP1L3MBTL1HDAC8HDAC1 | |
| SCHEMBL3891073 | 0.87 | HDAC8 (0.55) | GAATDP1L3MBTL1HDAC8HDAC1 | |
| SCHEMBL10772675 | 0.87 | GAA (0.54) | GAATDP1L3MBTL1HDAC8HDAC1 | |
| SCHEMBL3892218 | 0.87 | HDAC8 (0.55) | GAATDP1L3MBTL1HDAC8HDAC1 | |
| SCHEMBL4650738 | 0.84 | GAA (0.49) | GAATDP1L3MBTL1HDAC8HDAC1 | |
| SCHEMBL23935770 | 0.83 | L3MBTL1 (0.53) | GAATDP1L3MBTL1HDAC8HDAC1 | |
| SCHEMBL10768782 | 0.83 | MEN1 (0.63) | GAATDP1L3MBTL1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017919-A | Compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0887340-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 1998-12-30 | — | — | EP | disclosed |