Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | TDO2 | P48775 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14925385 | 0.89 | TSHR (0.54) | L3MBTL1GAATDP1IDO1TDO2 | |
| SCHEMBL14925384 | 0.87 | IDO1 (0.47) | L3MBTL1GAATDP1THRATHRB | |
| SCHEMBL15076021 | 0.84 | THRA (0.61) | L3MBTL1TDP1THRATHRBMEN1 | |
| SCHEMBL2258007 | 0.83 | IDO1 (0.55) | L3MBTL1IDO1TDO2MEN1KMT2A | |
| SCHEMBL8078006 | 0.83 | GAA (0.67) | L3MBTL1GAATDP1THRATHRB | |
| SCHEMBL10599678 | 0.83 | GAA (0.67) | L3MBTL1GAATDP1THRATHRB | |
| SCHEMBL11226516 | 0.83 | HTR7 (0.53) | THRATHRBMEN1KMT2AHDAC1 | |
| SCHEMBL10600889 | 0.83 | GAA (0.67) | L3MBTL1GAATDP1THRATHRB | |
| SCHEMBL9085161 | 0.83 | KMT2A (0.61) | IDO1TDO2MEN1KMT2AKDM4E | |
| SCHEMBL5311917 | 0.82 | HDAC8 (0.66) | L3MBTL1IDO1TDO2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3896056-A1 | AMINO ACID HAVING FUNCTIONAL GROUP CAPABLE OF INTERMOLECULAR HYDROGEN BONDING, PEPTIDE COMPOUND CONTAINING SAME AND METHOD FOR PRODUCTION THEREOF | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2021-10-20 | — | — | EP | disclosed |