Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL249159 | 0.80 | GAA (0.55) | GAATDP1L3MBTL1HTTALDH1A1 | |
| SCHEMBL29350104 | 0.79 | PSEN1 (0.40) | GAATDP1L3MBTL1HTTALDH1A1 | |
| SCHEMBL7243005 | 0.78 | GAA (0.54) | GAATDP1L3MBTL1HTTALDH1A1 | |
| SCHEMBL1856050 | 0.78 | GAA (0.54) | GAATDP1L3MBTL1HTTALDH1A1 | |
| SCHEMBL3914501 | 0.78 | GAA (0.54) | GAATDP1L3MBTL1HTTALDH1A1 | |
| SCHEMBL1681770 | 0.78 | GAA (0.54) | GAATDP1L3MBTL1HTTALDH1A1 | |
| SCHEMBL25254136 | 0.77 | PRKDC (0.53) | TDP1L3MBTL1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4947216 | 0.77 | ALDH1A1 (0.71) | GAATDP1L3MBTL1HTTALDH1A1 | |
| SCHEMBL8078045 | 0.77 | PTPN11 (0.55) | CNR1CNR2CYP2C9LMNATHRA | |
| SCHEMBL28421317 | 0.77 | LMNA (0.46) | GAATDP1L3MBTL1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017919-A | Compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0887340-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 1998-12-30 | — | — | EP | disclosed |