Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 16/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 9/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7713209 | 0.83 | PTGIR (0.67) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL8078275 | 0.78 | PTGIR (0.48) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL8078053 | 0.73 | PTGIR (0.43) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL8082944 | 0.72 | PTGIR (0.63) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL8078028 | 0.72 | PTGIR (0.49) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL8081130 | 0.68 | PTGIR (0.49) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7716647 | 0.66 | PTGIR (0.50) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7777382 | 0.65 | PTGIR (0.59) | PTGIRPTGDRPTGER3PTGER1CHRM4 | |
| SCHEMBL8080971 | 0.64 | PTGIR (0.61) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL6519312 | 0.64 | PTGIR (0.72) | PTGIRPTGDRPTGER3PTGER1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1030834-A1 | BENZOCYCLOHEPTENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999024397-A1 | BENZOCYCLOHEPTENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-05-20 | — | — | WO | disclosed |