Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 8/20 | 0.61 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717829 | 0.85 | PTGIR (0.65) | PTGIRPTGDRPTGER1PTGER3CHRM3 | |
| SCHEMBL7718277 | 0.81 | PTGIR (0.89) | PTGIRPTGDRPTGER1PTGER3PTGER4 | |
| SCHEMBL8078053 | 0.79 | PTGIR (0.43) | PTGIRPTGDRPTGER1PTGER3CHRM3 | |
| SCHEMBL8082944 | 0.76 | PTGIR (0.63) | PTGIRPTGDRPTGER1PTGER3CHRM3 | |
| SCHEMBL7779787 | 0.76 | PTGIR (1.00) | PTGIRPTGDRPTGER1PTGER3PTGER4 | |
| SCHEMBL7720284 | 0.76 | PTGIR (0.61) | PTGIRPTGDRPTGER1PTGER3 | |
| SCHEMBL8078275 | 0.74 | PTGIR (0.48) | PTGIRPTGDRPTGER1PTGER3CHRM3 | |
| SCHEMBL7778581 | 0.72 | PTGIR (0.81) | PTGIRPTGDRPTGER1PTGER3 | |
| SCHEMBL8068504 | 0.72 | BLM (0.54) | PTGIRPTGDRPTGER1PTGER3CHRM3 | |
| SCHEMBL9017290 | 0.71 | PTGIR (0.44) | PTGIRPTGDRPTGER1PTGER3CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1030834-A1 | BENZOCYCLOHEPTENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999024397-A1 | BENZOCYCLOHEPTENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-05-20 | — | — | WO | disclosed |