Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.98 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.98 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pranoprofen SCHEMBL5936565 | 0.99 | PTGS1 (1.00) | PTGS1ABCC4PTGS2POLBMAPT | |
| Pranoprofen SCHEMBL30315839 | 0.99 | PTGS1 (1.00) | PTGS1ABCC4PTGS2POLBMAPT | |
| Pranoprofen SCHEMBL30509656 | 0.99 | PTGS1 (1.00) | PTGS1ABCC4PTGS2POLBMAPT | |
| Pranoprofen SCHEMBL25783945 | 0.99 | PTGS1 (1.00) | PTGS1ABCC4PTGS2POLBMAPT | |
| Pranoprofen SCHEMBL29652156 | 0.99 | PTGS1 (1.00) | PTGS1ABCC4PTGS2POLBMAPT | |
| Pranoprofen SCHEMBL29385910 | 0.99 | PTGS1 (1.00) | PTGS1ABCC4PTGS2POLBMAPT | |
| Pranoprofen SCHEMBL26008 | 0.99 | PTGS1 (1.00) | PTGS1ABCC4PTGS2POLBMAPT | |
| Pranoprofen SCHEMBL29089048 | 0.98 | PTGS1 (0.98) | PTGS1ABCC4PTGS2POLBMAPT | |
| Pranoprofen SCHEMBL28338444 | 0.98 | PTGS1 (0.98) | PTGS1ABCC4PTGS2POLBMAPT | |
| Pranoprofen SCHEMBL29157937 | 0.93 | PTGS1 (0.89) | PTGS1ABCC4PTGS2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053749-B | Pranoprofen derivative and preparation method and application thereof | 许庆 | 2021-04-30 | — | — | CN | disclosed |
| CN-109053749-B | Pranoprofen derivative and preparation method and application thereof | 许庆 | 2021-04-30 | — | — | CN | disclosed |
| CN-109053749-A | A kind of pranoprofen derivative and its preparation method and application | 成都译山生物科技有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-109053749-A | A kind of pranoprofen derivative and its preparation method and application | 成都译山生物科技有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-101056855-A | Nitrogen-containing heterocyclic derivative and drug containing same as active ingredient | ONO PHARMACEUTICAL CO (JP) | 2007-10-17 | — | — | CN | disclosed |
| EP-0622072-B1 | Stable aqueous dispersions containing liposomes | WAKAMOTO PHARMA CO LTD (JP) | 2000-09-06 | — | — | EP | disclosed |
| US-5569464-A | ENCAPSULATING DRUGS | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1996-10-29 | — | — | US | disclosed |
| EP-0622072-A2 | Stable aqueous dispersions containing liposomes | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1994-11-02 | — | — | EP | disclosed |